A new study by Harischandra and colleagues which appear in Science Signaling suggests that manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein which is implicated in Parkinson's disease. Welders exposed to manganese were found to have increased misfolded α-synuclein in their serum exosomes.
These novel findings shed light on a previously unrecognized mechanism via which manganese can exacerbate and unmask latent idiopathic Parkinson's disease.
Link to original peer reviewed publication
These novel findings shed light on a previously unrecognized mechanism via which manganese can exacerbate and unmask latent idiopathic Parkinson's disease.
Link to original peer reviewed publication
RSS Feed
