These novel findings shed light on a previously unrecognized mechanism via which manganese can exacerbate and unmask latent idiopathic Parkinson's disease.
Link to original peer reviewed publication
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Neurotoxicants.com, website of Dr. Marcia Ratner, expert, neurotoxicologist consulting in neurotoxicology, neurotoxins, neurotoxicants, and neurodegenerative disease |
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A new study by Harischandra and colleagues which appear in Science Signaling suggests that manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein which is implicated in Parkinson's disease. Welders exposed to manganese were found to have increased misfolded α-synuclein in their serum exosomes.
These novel findings shed light on a previously unrecognized mechanism via which manganese can exacerbate and unmask latent idiopathic Parkinson's disease. Link to original peer reviewed publication
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A study by Goutman and colleagues which appears in the Journal of Neurology Neurosurgery and Psychiatry finds that higher plasma levels of persistent environmental pollutants is a risk factor in the progression of ALS.
These findings indicate that environmental exposures to toxicants plays a role in the progression of neurodegenerative disease such as ALS. Link to original news report in Science Daily Link to publication |
AuthorDr. Marcia Ratner shares and reviews the news. Archives
January 2025
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