According to a new study, entitled "Amyotrophic lateral sclerosis-like superoxide dismutase 1 proteinopathy is associated with neuronal loss in Parkinson’s disease brain" by Dr. Kay Double and colleagues at the University of Sydney, Australia, the SOD1 which has been implicated in Amyotrophic Lateral Sclerosis mayday also play a role in the pathogenesis of Parkinson’s Disease.
The story also quotes Dr. Double, who said, "We believe this loss of neurons results from a combination of oxidative stress [cell damage] and a regional deficiency in copper, both of which occur specifically in vulnerable regions of the Parkinson’s disease brain."
These data and others continue to implicate genetic and environmental factors that contribute to oxidative stress in the pathogenesis of neurodegenerative disease and emphasize the need for identifying those at risk early when efforts to reduce oxidative stress have the greatest potential to slow subclinical disease progression and forestall the emergence of debilitating clinically overt symptoms.
Link to original story by Dr. Joana Fernandes in Parkinson's News Today
Link to original per reviewed article.
The story also quotes Dr. Double, who said, "We believe this loss of neurons results from a combination of oxidative stress [cell damage] and a regional deficiency in copper, both of which occur specifically in vulnerable regions of the Parkinson’s disease brain."
These data and others continue to implicate genetic and environmental factors that contribute to oxidative stress in the pathogenesis of neurodegenerative disease and emphasize the need for identifying those at risk early when efforts to reduce oxidative stress have the greatest potential to slow subclinical disease progression and forestall the emergence of debilitating clinically overt symptoms.
Link to original story by Dr. Joana Fernandes in Parkinson's News Today
Link to original per reviewed article.
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