Holmes tremor in a worker with occupational carbon monoxide poisoning

I am pleased to share our most recent publication which appears in the America Journal of Industrial Medicine titled "A rare case of Holmes tremor in a worker with occupational carbon monoxide poisoning".  In this report we present a rare case of toxic encephalopathy and Holmes-type tremor, in a previously healthy 53-year-old man who was exposed to carbon monoxide while using a concrete saw in a small unventilated space.  Holmes tremor is characterized by resting, as well as postural and kinetic/intentional components. Specific lesions sites associated with Holmes tremor include the cerebellum, red nucleus, thalamus, and globus pallidus.  The globus pallidus is also vulnerable to carbon monoxide poisoning.  This patient's symptoms were ameliorated with the D2 preferring dopamine receptor agonist ropinirole.   This case report serves as reminder of the dangers associated with exposure to carbon monoxide in occupational settings.

Link to citation in PubMed