A new prospective cohort study by Diana Younan and colleagues published in the journal Neurology has found that older women without dementia who are exposed later in life to air pollution consisting of microscopic particles of chemicals, smoke, dust and other pollutants < 2.5 μm in diameter have an increased risk for neuroanatomical changes associated with Alzheimer's disease (AD). The study used MRI data combined with supervised machine learning to measure brain atrophy in areas vulnerable to AD. The observed increased risk could not be explained by geographic region; race; ethnicity; highest education level obtained; smoking or alcohol use; physical activity; BMI scores; diabetes; use of hormone replacement therapy nor by an MRI-measure of cerebrovascular damage.
These data add to the growing body of literature implicating exposure to neurotoxicants in the neuropathogenesis of neurodegenerative diseases such as AD.
Link to original article
These data add to the growing body of literature implicating exposure to neurotoxicants in the neuropathogenesis of neurodegenerative diseases such as AD.
Link to original article
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