A team of researchers from UCLA has reported on an association between occupational pesticide exposure and increased risk for PD. The study known as the Parkinson Environment Gene (PEG) study showed that risk was increased with occupational exposure to various classes of pesticides, indicating that no specific chemical but rather a shared mechanism of action may be involved. Unfortunately, this study lacked the statistical power to examine gene-pesticide interactions. Risk increased with increasing years of pesticide use, and job tasks resulting in the highest exposures to pesticides such as mixing and loading pesticides. These new findings are consistent with those reported by Ratner et al., 2015 and lend further support to the growing body of literature indicating that PD risk is modified by chemical exposures at concentrations that typically occur in occupational settings and that there is a dose response relationship between exposure and disease risk.
Link to study on PubMed
Link to study on PubMed
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